IsoDynamic is delighted to announce they have been selected to assist in the development of a Web application by Dr. Brian Lindman, Assistance Professor of Medicine, Cardiovascular Division, in the medical school at Washington University in St. Louis.  The application will assist doctors and patients in the decision process for the Trans-Catheter Aortic Valve Replacement (TAVR) procedure.

Dr. Lindman has received a grant from the National Institute of Health to develop a quantitative risk prediction model of TAVR outcomes based on a variety of risk factors and biomarkers.  He and his team will look at data from traditional risk factors such as age, BMI, lung disease, and gender.  He will also look at novel risk factors such as frailty (as determined by the ability to walk, 5 meter walk time, etc.) and additional biomarkers.  After collecting data over a significant period, he will use quantitave methods to determine which factors are predictive of outcomes such as survival and quality of life.  

After these factors are determined, IsoDynamic will collaborate with Dr. Lindman to develop a Web application that allows doctors to enter patient risk factors.  They will in turn receive graphical outputs that can be shared with patients during an informed decision making process.  The outputs will show survival rate and qualitify of life outcomes at various time intervals.

"We are very excited to be working with Dr. Lindman," says Kraig Robson, President and founder of IsoDynamic.  "Dr. Lindman has already distinguished himself by securing funding from NIH in an extremely competitive funding environment.  It's a reflection of the outstanding idea he has developed, to not just determine the major risk factors for TAVR, but developing a process whereby physicians can consult with patients to make an informed decision.  We are honored to have been chosen by Dr. Lindman, and we look forward to extending our ongoing work with Washington University in St. Louis to improve patient outcomes."